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Diclofenac is a common anti-inflammatory drug administered to livestock and is used to treat the symptoms of inflammation, fevers and/or pain associated with disease or wounds.But today, most are in danger of extinction due to a veterinary drug called diclofenac (vultures do not have a particular enzyme to break down diclofenac). Nine species of vulture can be found living in India.India has a high species diversity and hence vultures get lot of food.


īusiness standard (2020) dated 13th April 2020. J AOAC Int 86(2):412–431īirdLife International (2020) Species factsheet: Gyps bengalensis. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.Īnastassiades M, Lehotay SJ, Štajnbaher D, Schenck FJ (2003) Fast and easy multiresidue method employing acetonitrile extraction/partitioning and “dispersive solid-phase extraction” for the determination of pesticide residues in produce. Further, an effective system is recommended to be put in place to collect the tissues of dead vultures for toxicological investigations and eventual conservation of the critically endangered species.Įndangered species Forensic analysis NSAID Pesticide Toxicological investigations Vulture. Hence, it is recommended that nimesulide should be banned by the government to conserve white-rumped vulture in the Indian subcontinent. Since, nimesulide appears to act similar to diclofenac in exerting toxic effects, if veterinary use of nimesulide continues, white-rumped vulture are bound to suffer. Although, other than diclofenac, many NSAIDs are suspected to be toxic to white-rumped vultures, only nimesulide is reported in the recent past with clear symptom of gout in wild dead white-rumped vultures similar to diclofenac. Residues of nimesulide in tissues with symptoms of gout indicated that the vultures died due to nimesulide poisoning. Visceral gout was also observed in all the four vultures during post-mortem. Of all the drugs tested, only nimesulide was detected in all the tissues (17-1395 ng/g) indicative of exposure. Subsequently, the tissues were analysed for thirteen NSAIDs and paracetamol. Tissues were screened for a set of toxic pesticides, and none of them was at detectable level. After post-mortem examinations, tissues of all four vultures were received for toxicological investigation at the National Centre for Avian Ecotoxicology, SACON. During 2019, there were two known separate incidents of white-rumped vulture mortality involving four white-rumped vultures in Gujarat. Population of white-rumped vulture has not recovered in India to a desired level even after diclofenac was banned in 2006.
